[HTML][HTML] Circulating cytokines and chemokines associated with plasma leakage and hepatic dysfunction in Brazilian children with dengue fever

RAX Ferreira, SA de Oliveira, M Gandini… - Acta tropica, 2015 - Elsevier
Dengue fever is usually a benign acute viral infection transmitted by arthropods but may
evolve to severe clinical manifestations such as coagulation and/or hemodynamic disorders,
caused mainly by an increase of vascular permeability. Deregulated circulating
immunological factors have been associated with severity. In Brazil severe cases appeared
in children only recently and we evaluated the profile of cytokine/chemokine kinetics in 134
hospitalized young patients during the epidemic in Rio de Janeiro in 2008. Inflammatory …