[PDF][PDF] Combination cancer therapies with immune checkpoint blockade: convergence on interferon signaling

AJ Minn, EJ Wherry - Cell, 2016 - cell.com
Cell, 2016cell.com
Improving efficacy of immune checkpoint blockade for cancer can be facilitated by
combining these agents with each other and/or with other conventional or targeted
therapies. Interferon and innate immune signaling pathways in immune and tumor cells
have emerged as intriguing determinants of response and resistance, often in complex and
seemingly paradoxical ways.
Improving efficacy of immune checkpoint blockade for cancer can be facilitated by combining these agents with each other and/or with other conventional or targeted therapies. Interferon and innate immune signaling pathways in immune and tumor cells have emerged as intriguing determinants of response and resistance, often in complex and seemingly paradoxical ways.
cell.com