Hepatitis B vaccination in pregnancy: factors influencing efficacy

CJ Ingardia, L Kelley, JD Steinfeld, JR Wax - Obstetrics & Gynecology, 1999 - Elsevier
Objective: To determine seroprotective antibody response after hepatitis B vaccination
during pregnancy and to assess factors influencing the rate of maternal seroprotection.
Methods: Records of 80 healthy gravidas who elected hepatitis B vaccination during
pregnancy, after being identified as hepatitis B surface antigen (HbsAg) and antibody
(HbsAb) negative on initial prenatal screen, were analyzed retrospectively. Each gravida
was begun on a series of three recombinant hepatitis B vaccines at 0, 1, and 6 months. At 36 …