Connections between events occurring in early life with adult asthma suggest that both the
altered regulation of airway caliber and tone and the changes in airway structure present in
many asthma cases may have their roots in developmental patterns established during
infancy and childhood. The Melbourne epidemiologic study, the British 1958 birth cohort,
and the Tasmanian asthma survey all provide important information on the outcomes of
childhood asthma in later life. Among the findings, these studies showed that in a large …