[HTML][HTML] Distribution, interconversion, and dose response of n− 3 fatty acids in humans

LM Arterburn, EB Hall, H Oken - The American journal of clinical nutrition, 2006 - Elsevier
ABSTRACT n− 3 Fatty acids have important visual, mental, and cardiovascular health
benefits throughout the life cycle. Biodistribution, interconversion, and dose response data
are reviewed herein to provide a basis for more rational n− 3 dose selections.
Docosahexaenoic acid (DHA) is the principal n− 3 fatty acid in tissues and is particularly
abundant in neural and retinal tissue. Limited storage of the n− 3 fatty acids in adipose
tissue suggests that a continued dietary supply is needed. A large proportion of dietary α …