Young investigators are entering the physician-scientist workforce (PSW) at a rate that is insufficient to maintain it (1), threatening the future of a group that plays a vital role in medical progress. New physician-scientists are the products of a training pipeline that encompasses many possible pathways that vary widely in organization and timing of research training. Additionally, within individual pathways, program organization and trainee support differ considerably across phases of training. This complexity leads to training experiences fraught with challenges and uncertainties that may provoke attrition. Thus, leaders in the physicianscientist community have pointed to the training pipeline itself as the bearer of considerable responsibility for the problematic trends facing the PSW (2). To address these issues, Milewicz et al. proposed action items aimed at increasing trainee numbers and diversity, providing broad support throughout training, and decreasing the total time spent in the pipeline (3). This roadmap for improving physician-scientist training has generated substantial discussion about how training programs, institutions, and professional organizations can implement its recommendations. However, notably absent from these discussions has been a role for trainee-driven approaches. As arguably the greatest stakeholders, we, as current physician-scientist trainees, are devoted to being a part of the solution. Here, we present actions we are taking to bolster the front end of the physician-scientist pipeline through initiatives of the American Physician Scientists Association (APSA). APSA is a trainee-led national professional organization that has been dedicated to serving physician-scientists in training for more than a decade (4). Members of APSA are MD, DO, and dual-degree trainees as well as residents and fellows pursuing careers as physician-scientists. The mission of APSA is to provide trainees with a platform for advancing physicianscientist training and advocating for the future of translational medicine. In this role, APSA brings together trainees from across the country to collaborate on research efforts and initiatives aimed toward our training and future careers. Following publication of the NIH Physician-Scientist Workforce Working Group Report in 2014 (1), APSA leaders considered actions the organization can take to be a part of the solution to issues identified within the PSW. APSA’s membership has both intimate experience with the current training environment and past experience as undergraduate students considering future careers as physician-scientists. Thus, APSA is uniquely positioned to take action at the front end of the physicianscientist pipeline with the goals of increasing both the number and the diversity of students entering physician-scientist training and supporting trainees during medical school or dual-degree programs.