[HTML][HTML] The tetraspan protein epithelial membrane protein-2 interacts with β1 integrins and regulates adhesion
M Wadehra, R Iyer, L Goodglick, J Braun - Journal of Biological Chemistry, 2002 - ASBMB
The growth arrest-specific-3 (GAS3)/PMP22 proteins are members of the four-
transmembrane (tetraspan) superfamily. Although the function of these proteins is poorly
understood, GAS3/PMP22 proteins have been implicated in the control of growth and
progression of certain cancers. Epithelial membrane protein-2 (EMP2), a GAS3/PMP22
family member, was recently identified as a putative tumor suppressor gene. Here, we
addressed the normal function of EMP2 by testing the prediction that it influences integrin …
transmembrane (tetraspan) superfamily. Although the function of these proteins is poorly
understood, GAS3/PMP22 proteins have been implicated in the control of growth and
progression of certain cancers. Epithelial membrane protein-2 (EMP2), a GAS3/PMP22
family member, was recently identified as a putative tumor suppressor gene. Here, we
addressed the normal function of EMP2 by testing the prediction that it influences integrin …