[HTML][HTML] Structural and nonstructural viral proteins are targets of T-helper immune response against human respiratory syncytial virus

E Lorente, A Barriga, E Barnea, C Mir, JA Gebe… - Molecular & Cellular …, 2016 - ASBMB
Proper antiviral humoral and cellular immune responses require previous recognition of viral
antigenic peptides that are bound to HLA class II molecules, which are exposed on the
surface of antigen-presenting cells. The helper immune response is critical for the control
and the clearance of human respiratory syncytial virus (HRSV) infection, a virus with severe
health risk in infected pediatric, immunocompromised, and elderly populations. In this study,
using a mass spectrometry analysis of complex HLA class II-bound peptide pools that were …