[HTML][HTML] The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against …
Confocal microscopy images revealed that the tetratricopeptide repeat motif (TPR) domain
immunophilin FKBP51 shows colocalization with the specific mitochondrial marker
MitoTracker. Signal specificity was tested with different antibodies and by FKBP51
knockdown. This unexpected subcellular localization of FKBP51 was confirmed by
colocalization studies with other mitochondrial proteins, biochemical fractionation, and
electron microscopy imaging. Interestingly, FKBP51 forms complexes in mitochondria with …
immunophilin FKBP51 shows colocalization with the specific mitochondrial marker
MitoTracker. Signal specificity was tested with different antibodies and by FKBP51
knockdown. This unexpected subcellular localization of FKBP51 was confirmed by
colocalization studies with other mitochondrial proteins, biochemical fractionation, and
electron microscopy imaging. Interestingly, FKBP51 forms complexes in mitochondria with …