[HTML][HTML] Differences in the regulation of adipose tissue and liver lipogenesis by carbohydrates in humans

F Diraison, V Yankah, D Letexier, E Dusserre… - Journal of lipid …, 2003 - ASBMB
We assessed the contributions of human liver and adipose tissue de novo lipogenesis
(DNL) to triacylglycerol (TAG) synthesis. Volunteers were fed a high-energy, high-
carbohydrate diet (HC, n= 5) or a normocaloric diet (NC, n= 10). NC subjects remained in
the fasting state (Study 1, n= 5) or received oral glucose (Study 2, n= 5) throughout the test
(12 h). HC subjects remained in the fasting state (Study 3). They ingested deuterated water
and [U-13 C] acetate to trace lipogenesis. Adipose tissue fatty-acid (FA) synthase (FAS) …