Patient-paired sample congruence between 2 commercial liquid biopsy tests

G Torga, KJ Pienta - JAMA oncology, 2018 - jamanetwork.com
Methods| From January 2017 to July 2017 samples from 40 patients with metastatic prostate
cancer were collected at the same time serially via a single blood draw and shipped
overnight to 2 different Clinical Laboratory Improvement Amendments (CLIA)-licensed,
College of American Pathologistsaccredited laboratories for cfDNA next-generation
sequencing following the instructions of each vendor. Guardant360 (Guardant Health, Inc)
panel includes 73 genes with complete exon sequencing for 19 cancer genes, critical exons …