[HTML][HTML] Phospholipid flippase ATP10A translocates phosphatidylcholine and is involved in plasma membrane dynamics
T Naito, H Takatsu, R Miyano, N Takada… - Journal of Biological …, 2015 - ASBMB
We showed previously that ATP11A and ATP11C have flippase activity toward
aminophospholipids (phosphatidylserine (PS) and phosphatidylethanolamine (PE)) and
ATP8B1 and that ATP8B2 have flippase activity toward phosphatidylcholine (PC)(Takatsu,
H., Tanaka, G., Segawa, K., Suzuki, J., Nagata, S., Nakayama, K., and Shin, HW (2014) J.
Biol. Chem. 289, 33543–33556). Here, we show that the localization of class 5 P4-ATPases
to the plasma membrane (ATP10A and ATP10D) and late endosomes (ATP10B) requires an …
aminophospholipids (phosphatidylserine (PS) and phosphatidylethanolamine (PE)) and
ATP8B1 and that ATP8B2 have flippase activity toward phosphatidylcholine (PC)(Takatsu,
H., Tanaka, G., Segawa, K., Suzuki, J., Nagata, S., Nakayama, K., and Shin, HW (2014) J.
Biol. Chem. 289, 33543–33556). Here, we show that the localization of class 5 P4-ATPases
to the plasma membrane (ATP10A and ATP10D) and late endosomes (ATP10B) requires an …
