Do nitric oxide and cGMP play a role in calcium cycling?
EA Milbourne, FL Bygrave - Cell Calcium, 1995 - Elsevier
The biological molecule NO and its cyclic nucleotide effector molecule cGMP, are involved
in a variety of biological systems. This article reviews evidence supporting a role for these
molecules in signal transduction. Over the last 10 years, it has become evident that these
molecules are important in Ca2+ regulation, particularly in excitable cells. In these cells,
cGMP-dependent mechanisms appear to both directly and indirectly regulate Ca2+
transport. Until recently, reports of the actions of cGIVIP in non-excitable cells have been …
in a variety of biological systems. This article reviews evidence supporting a role for these
molecules in signal transduction. Over the last 10 years, it has become evident that these
molecules are important in Ca2+ regulation, particularly in excitable cells. In these cells,
cGMP-dependent mechanisms appear to both directly and indirectly regulate Ca2+
transport. Until recently, reports of the actions of cGIVIP in non-excitable cells have been …
