Vaccination with Haemophilus influenzae type b meningococcal protein conjugate vaccine reduces oropharyngeal carriage of Haemophilus influenzae type b among …
AK Takala, M Santosham, J Almeido-Hill… - The Pediatric …, 1993 - journals.lww.com
AK Takala, M Santosham, J Almeido-Hill, M Wolff, W Newcomer, R Reid, H Käyhty, E Esko…
The Pediatric infectious disease journal, 1993•journals.lww.comThe effect of Haemophilus influenzae type b (Hib) meningococcal protein conjugale vaccine
(Hib-OMPC; Merck, Sharp & Dohme) on oropharyngeal (OP) carriage of Hib was evaluated
in Navajo and Apache Indian children, who are known to be at high risk for invasive Hib
disease. We obtained 1423 OP swabs at well child visits from 1321 children 3 months to 4
years of age: 293 of the swabs were obtained from children before the administration of any
Hib-OMPC; 1119 were taken after the primary vaccination series; and 11 after the booster …
(Hib-OMPC; Merck, Sharp & Dohme) on oropharyngeal (OP) carriage of Hib was evaluated
in Navajo and Apache Indian children, who are known to be at high risk for invasive Hib
disease. We obtained 1423 OP swabs at well child visits from 1321 children 3 months to 4
years of age: 293 of the swabs were obtained from children before the administration of any
Hib-OMPC; 1119 were taken after the primary vaccination series; and 11 after the booster …
Abstract
The effect of Haemophilus influenzae type b (Hib) meningococcal protein conjugale vaccine (Hib-OMPC; Merck, Sharp & Dohme) on oropharyngeal (OP) carriage of Hib was evaluated in Navajo and Apache Indian children, who are known to be at high risk for invasive Hib disease. We obtained 1423 OP swabs at well child visits from 1321 children 3 months to 4 years of age: 293 of the swabs were obtained from children before the administration of any Hib-OMPC; 1119 were taken after the primary vaccination series; and 11 after the booster dose. Swabs were tested for the presence of Hib capsular polysaccharide antigen by enzyme-linked immunosorbent assay. Forty of 1423 swabs were positive for Hib. Among the 40 positive swabs 5 (13%) were obtained from children who
Lippincott Williams & Wilkins